Organic Chemistry II — Chapter Study Guide

CHAPTER GUIDE / ORGANIC CHEMISTRY

Organic Chemistry II

Selected guide: Smith — Organic Chemistry, 2026 release. McGraw Hill · 2026 release, Janice Gorzynski Smith.

Follow Smith’s Organic Chemistry (2026) sequence for radicals, aromatic compounds, carbonyl chemistry, synthesis, and more. The coverage in your class may differ.

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Course boundaries vary by institution. If your instructor assigns chapters outside this list, continue in the Smith Organic Chemistry I chapter map.

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These links are original IntoChemistry companion explanations and practice, not reproduced textbook chapters. The chapters assigned in your course may vary by instructor or semester.

Chapter-by-chapter resources

Chapter 13: Radical Reactions

Radical formation, propagation and radical reaction patterns.

Chapter 14: Conjugation, Resonance, and Dienes

Delocalization and conjugated systems.

Chapter 15: Benzene and Aromatic Compounds

Aromaticity, aromatic systems and benzene structure.

Chapter 16: Reactions of Aromatic Compounds

Aromatic substitution and reaction planning.

Chapter 17: Introduction to Carbonyl Chemistry: Organometallic Reagents; Oxidation and Reduction

Carbonyl structure, organometallic chemistry and redox strategies.

Chapter 18: Aldehydes and Ketones—Nucleophilic Addition

Nucleophilic addition, hemiacetals, imines and carbonyl mechanisms.

Chapter 19: Carboxylic Acids and Nitriles

Carboxylic acid reactions, nitriles and acidity.

Chapter 20: Carboxylic Acids and Their Derivatives—Nucleophilic Acyl Substitution

Acid derivatives and acyl substitution mechanisms.

Chapter 21: Substitution Reactions of Carbonyl Compounds at the α-Carbon

Alpha-carbon reactions and carbonyl enolate chemistry.

Chapter 22: Carbonyl Condensation Reactions

Aldol and related carbonyl condensation concepts.

Chapter 23: Amines

Nitrogen-containing organic compounds and reactions.

Chapter 24: Carbon–Carbon Bond-Forming Reactions in Organic Synthesis

Multistep synthesis, new C–C bond formation and retrosynthesis.

Chapter 25: Pericyclic Reactions

Concerted pathways and cycloaddition foundations.

Chapter 26: Carbohydrates

Carbohydrate structure, stereochemistry and chemistry.

Chapter 27: Amino Acids and Proteins

Functional groups, peptide chemistry and biochemistry context.

Chapter 28: Nucleic Acids and Protein Synthesis

Structure and chemical properties of biological macromolecules.

Chapter 29: Lipids (online chapter)

Hydrophobic biomolecules and their structures.

Chapter 30: Metabolism (online chapter)

Organic chemistry reactions in biochemical pathways.

Chapter 31: Synthetic Polymers (online chapter)

Polymer structure and materials applications.

Other study options

Use Carbonyl Chemistry, Synthesis Planning and Spectroscopy Challenges. For research and applications read the independent Chemistry Blog.