Organic Chemistry I — Chapter Study Guide

CHAPTER GUIDE / ORGANIC CHEMISTRY

Organic Chemistry I

Selected guide: Smith — Organic Chemistry, 2026 release. McGraw Hill · 2026 release, Janice Gorzynski Smith.

Companion lessons for Smith’s Organic Chemistry (2026): structure, acids and bases, stereochemistry, mechanisms, alkenes, alkynes, and spectroscopy.

← Choose a different textbook · Browse every lesson · Chemistry Blog

Course boundaries vary by institution. If your instructor assigns chapters outside this list, continue in the Smith Organic Chemistry II chapter map.

Glassware with colorful molecular models

Find your textbook chapter

Jump to: 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · Spec A · Spec B · Spec C · 13

These links are original IntoChemistry companion explanations and practice, not reproduced textbook chapters. The chapters assigned in your course may vary by instructor or semester.

Chapter-by-chapter resources

Chapter 1: Structure and Bonding

Bonding, Lewis structures, atomic orbitals, formal charge and resonance.

Chapter 2: Acids and Bases

Organic acid–base reasoning, conjugate pairs and factors affecting relative acidity.

Chapter 3: Introduction to Organic Molecules and Functional Groups

Recognize functional groups and interpret molecular structures.

Chapter 4: Alkanes

Conformations, Newmans, cyclohexane chairs and ring flips.

Chapter 5: Stereochemistry

Chirality, enantiomers and R/S configurations.

Chapter 6: Understanding Organic Reactions

Reaction arrows, bond changes, nucleophiles, electrophiles and mechanisms.

Chapter 7: Alkyl Halides and Nucleophilic Substitution

SN1/SN2 competition, solvents, leaving groups, kinetics and inversion.

Chapter 8: Alkyl Halides and Elimination Reactions

E1/E2 selection, stereochemistry and anti-periplanar geometry.

Chapter 9: Alcohols, Ethers, and Related Compounds

Alcohol reactions, ether formation, epoxides and synthesis.

Chapter 10: Alkenes and Addition Reactions

Regiochemistry, stereochemistry and alkene reactions.

Chapter 11: Alkynes and Synthesis

Triple-bond chemistry and retrosynthetic planning.

Chapter 12: Oxidation and Reduction

Alcohol oxidation, carbonyl reduction and redox reagents.

Spec A: Mass Spectrometry

Analyze masses and fragmentation with complementary evidence.

Spec B: Infrared Spectroscopy

Read IR bands and functional-group evidence.

Spec C: Nuclear Magnetic Resonance Spectroscopy

Chemical shifts, signal integration, splitting and structure evidence.

Chapter 13: Radical Reactions (bridge / if assigned)

Radical substitution and radical reaction pathways; Smith Chapter 13 may be covered in Organic I or II.

Other study options

For more focused problem practice use Mechanism Practice, Stereochemistry Outcomes and Organic Exam Prep. The Chemistry Blog remains separate, with relevant research articles appearing as optional reading.